Antibodies are supposed to be proteins that could be binding to certain molecules known as antigens. They possess different portions in their typical Y-shaped structure which could be binding to effector molecules and antigens. Numerous kinds of antibodies like secondary and primary and polyclonal and monoclonal antibodies with diverse specifications have come up in the past few years. Thanks to these developments, antibodies are regarded as indispensable in a host of applications in biomedical research and medicine.
Applications of Antibodies
Some Effective Diagnostic Applications
Antibodies play a pivotal role in medical diagnostics. Numerous biochemical assays help in the effective detection of certain antibodies for particularly, accurate diagnosis of diseases. Most of the immunodiagnostic techniques like ELISA would be using multiple antibodies for detecting certain antigens that could trigger infectious diseases.
As per http://www.biologydiscussion.com, monoclonal antibodies have radically changed the entire laboratory diagnosis of different diseases. Monoclonal antibodies could be used as diagnostic reagents associated with biochemical analysis. They could even be utilized as effective tools for accurate diagnostic imaging of various diseases. Antibodies could be used effectively in clinical immunology for the analysis of the antibody profile of a patient. A boost in some immunoglobulin may be an effective indicator in the proper diagnosis of several ailments such as a boost in IgM seems to be an important indicator of Viral Hepatitis. Antibodies could be utilized in various pregnancy test kits that are available over the counter.
Use of Antibodies in Therapy
Antibodies could be used for treating immune deficiencies like hypogammaglobulinemia. Here, readymade antibodies would be administered for inducing passive immunity. In this context, we know that monoclonal antibodies are used for treating numerous diseases like psoriasis, rheumatoid arthritis, multiple sclerosis, and different types of cancers including breast cancer and colorectal cancer.
Antibodies Are Useful in Biomedical Research
The high sensitivity and specificity of antibodies could prove to be hugely advantageous to biomedical research applications. Large scale production of antibodies could take place as a result of advancements in biotechnology.
Antibodies Are Effectively Used in Immunosorbent Assays
ELISAs or Enzyme-linked immunosorbent assays are supposed to be highly successful and popular techniques that are utilized for the detection and quantification of precise target antigens. We know that Direct ELISA would be using monoclonal antibodies for detecting a particular antigen present in a solution. Indirect ELISA would be using a secondary and primary antibody for detecting the antigen. Browse through Mybiosource.com for ELISA kits for detecting a host of proteins, antigens, and even peptides including VEGF, EGF, and diverse cytokines.
This technique involves the electrophoretic separation of proteins. The separated proteins are then transferred directly to any blotting paper that is exposed to antibodies for detecting the proteins.
Antibodies & their Role in Prenatal Therapy
Antibodies such as Rho (D) immune globulin are utilized in prenatal treatment for preventing hemolytic disease risk in the case of a newborn. If the mom is treated successfully with anti-RhD antibodies prior to delivery it would be destroying the Rh antigen contained in the fetus before the maternal B cells are stimulated by the antigens.
The role of antibodies simply cannot be undermined as they could be used effectively in treating numerous diseases including cancers, multiple sclerosis, rheumatoid arthritis, etc. They are used successfully for treating certain immune deficiencies. They are great for biomedical research.